Oral methotrexate and risk of unintentional overdose due to medication errors

26 aprile 2024 – Oral dosage forms of methotrexate are used in the treatment of inflammatory autoimmune diseases as a low single dose once weekly. Accidentally taking a dose daily that should be taken weekly can result in an overdose with serious consequences and possibly even be fatal.

As a side note Swissmedic has emphasised that in Switzerland, healthcare professionals who are authorised to dispense or administer medicinal products are obligated to report severe and/or previously unknown side effects. Reports to Swissmedic can be entered and sent in the Electronic Vigilance Reporting Portal “ElViS”.

For more information, see here.